Infrastructure

Pharmaceutical Development & Analytical Science

Oral solids, sterile products, ointments and topical semisolids, liquid orals and analytical science are developed on one site in Selaiyur, so a formulation question and the instrument that answers it are a corridor apart. Every instrument listed here is one our scientists work on.

Development and analytical laboratories: 5; Development and analytical laboratories
Process and analytical instruments: 35+V-24; Process and analytical instruments
Stability and photostability chambers: ICH; Stability and photostability chambers

Samples prepared under a laminar airflow unit — Selaiyur, Chennai5 laboratories · one site

Oral solid process lab

Granulation, pelletisation, compression and coating at bench and pilot scale.

Nine process routes can be tried on the same molecule and taken to pilot scale here, so the route is chosen on evidence rather than on what the laboratory happens to own.

Fluid bed processor (FBP) with top-spray and Wurster columns, ACG
Fluid bed dryer
Rotary compression: Cadmach 17-station and Karnavati 10-station, D and B tooling
Roll compactor
Extruder and spheroniser, Fuji Paudal
Air-jet mill; multi mill, Becto Chem
Octagonal blender (3 L, 7 L); double-cone blender (3 L, 5 L)
Auto-coating machine, Neocota; conventional coating pan
Encapsulation machine, MF 300
High-pressure homogeniser, GEA Niro Soavi Panda Plus; lab-scale homogeniser
Vibratory sifter, Becto Chem; sieve shaker, Electrolab
Blister pack machine; induction cap sealing machine
Moisture analyser, Mettler Toledo; tap density, disintegration and hardness testers

Sterile development lab

Injectables, emulsions and suspensions under controlled conditions.

Sterile formats from simple aqueous injections to nano-emulsions and lyophilised products are developed here, which is why complex parenterals do not have to be sent elsewhere mid-programme.

Manufacturing tanks, SS 316L (5–10 L)
High-pressure and high-speed homogenisers
Filtration tank and peristaltic pump
Autoclave
Laminar airflow unit
Sealer and de-sealer
Top-mounted stirrer; magnetic stirrer with heating
Microscope, up to 100× magnification
pH meter

Ointment / topical semisolid development lab

A dedicated Topical Semisolid Development Laboratory for the development and optimization of ointments, creams, gels, lotions and other dermatological formulations.

The facility supports pre-formulation, API–excipient compatibility, vehicle and base selection, formulation screening, homogenization, emulsification and process optimization. Development activities include optimization of critical formulation and process parameters, rheological and physical characterization, drug-content uniformity, in-vitro release testing (IVRT), stability studies and scale-up support. The laboratory is designed to support development of both conventional and complex topical formulations for generic and differentiated products.

Vehicle and base selection
Homogenization and emulsification
Rheological characterization
In-vitro release testing (IVRT)

Liquid oral development lab

A dedicated Oral Liquid Development Laboratory for formulation and process development of oral solutions, suspensions, emulsions, syrups and other liquid oral dosage forms.

The facility supports pre-formulation, solubility and compatibility studies, vehicle and excipient selection, pH and viscosity optimization, taste-masking, preservative-system development and formulation screening. It enables optimization of critical formulation and process parameters, including mixing, homogenization, suspension characteristics and physical stability. The laboratory also supports analytical evaluation, dissolution/release assessment where applicable, stability studies and scale-up for clinical, BE and commercial batches.

Solubility and compatibility studies
pH and viscosity optimization
Taste-masking
Preservative-system development

Analytical laboratory

Separation, mass spectrometry, elemental analysis and stability.

Impurities, residual solvents and elemental impurities are identified in the same building as the batch that produced them, so an analytical finding reaches the formulator the same week.

Liquid chromatography–tandem mass spectrometry (LC-MS/MS)
Gas chromatography–mass spectrometry (GC-MS)
Inductively coupled plasma mass spectrometry (ICP-MS)
Shimadzu HPLC with UV
Dionex ion chromatography
Dissolution apparatus, USP I, II and III (Electrolab), with autosampler
Franz diffusion apparatus
Temperature/humidity-controlled stability chambers and photostability chambers
UV and UV-visible spectrophotometers
Particle-size analyser, micron to nano
Karl Fischer titrator, viscometer, conductivity meter
Centrifuge, automatic shaker, sonicator

Science & technology

The science behind difficult-to-make products.

Much of our work sits where routine generic development stops: molecules that are unstable, poorly soluble, hard to deliver or demanding to handle.

Reformulations that solve a patient or supply problem.

Oral liquids made from tablets for children, ready-to-use injectables made from lyophilised powders, extended-release and orally disintegrating tablets, all designed on non-infringing routes.

Tablet → oral solution or suspension
Powder → ready-to-use injection
Immediate → extended release
Differentiated topicals

Solifenacin succinate, tablets reformulated as an oral suspension and solution for paediatric patients: 6-month stability completed.

Five ways to engage, one team behind each.

01
Dossier development
We develop the product and the dossier; you file it.
02
Dossier compilation
We turn development data you already hold into a submission-ready dossier.
03
Co-development
We share the development investment and the commercial return through profit sharing.
04
Technology transfer
We move a developed product into your plant or your chosen CMO.
05
Commercial supply
We supply finished product through a qualified manufacturing network.